Cationic Amphiphiles: Self-Assembling Systems for Biomedicine and Pharmacies

Author: Devnsky, Ferdinand

Edition: 1

Number Of Pages: 295

EAN: 9781536119794

Release Date: 02-06-2017

Languages: English

Binding: hardcover

Package Dimensions: 8.7 x 6.0 x 1.0 inches

Details: A special distinct class of surfactants is represented by a double-chain, double-head form of surfactant molecules, which are called gemini surfactants. Gemini surfactants show physicochemical and aggregation properties which are superior to those of conventional, single-chain surfactants. One of the most developing areas of cationic gemini surfactants application is the field of pharmaceutical applications. Interaction of cationic surfactants with the oppositely charged cell membrane has been known for a long time. Cationic gemini surfactants turned out to be very efficient bactericidal and antimicrobial agents. Moreover, recent development in this field indicates a cancerostatic effect of cationic geminis through a selective interaction of cationic gemini molecules with cancer cells. Another revolutionary field of cationic gemini surfactants application is their interaction with an oppositely charged electrolyte such as DNA. The interaction of DNA with various positively charged syst